What is Lyme Disease?

Lyme disease is caused by a bacteria that is transferred to humans through the bite of an infected tick. Anyone can get Lyme disease, but it is more common in children and teens.

People who get Lyme disease often get a red circular rash (called a "bullseye rash") around the tick bite and may feel tired, achy, and feverish.

In most cases, Lyme disease can be treated with antibiotics. If left untreated, the bacteria that causes Lyme disease can spread through bloodstream and cause serious problems in the brain, joints, and heart.

Right now, the best way to prevent Lyme disease is to prevent tick bites.

About The Study

The purpose of this study is to learn more about the safety of an investigational Lyme vaccine in people between the ages of 5-17 years old.

About 3,000 participants will be enrolled at study sites in the United States.

Why Consider Volunteering?

Currently, there are no approved vaccines available to prevent Lyme disease. Before a new vaccine can be approved, it must first be tested in a series of clinical trials, also known as research studies. All clinical trials are carefully designed and monitored to ensure the health and safety of the volunteers that make them possible.

Make an Important Contribution

By choosing to volunteer for this new study, participants could receive an investigational vaccine that may help to prevent Lyme disease. Participants will represent others like them — in age, gender, race, ethnicity, and from communities like their own. Including people from different backgrounds will help us develop a Lyme disease vaccine that is more likely to be effective for everyone.

Joining a clinical trial is an important, personal decision. Thank you for considering this study.

What To Expect

If your child or teen is interested in participating, the study team may schedule a pre-study visit to determine if this study is a good fit for him/her.

Eligible participants will be randomly assigned to receive the study vaccine or placebo (an injection that looks like the study vaccine but does not contain any active ingredients).

Participants are 3 times more likely to receive the study vaccine than placebo. Participants, parents, and doctors will not know which has been assigned.

Participants will receive 4 shots in the upper arm: 3 in the first 6 months, and a booster 1 year later.

Participants will be enrolled for about 2 years, including 6 planned in-office visits and 2 follow-up phone calls.

Participants may be reimbursed for study-related expenses like travel.

Before You Continue...

A first step as you consider this study is to answer a 5-minute online questionnaire about your health and medical history. If your answers show the study might be a good fit for your child, you may choose to be referred to a study clinic that you select. You will then be asked to provide your contact information for a study representative to contact you and discuss the next steps. Only the study staff can determine if you meet the study's eligibility criteria and are able to enroll in the study.

Click 'Next' to begin the questionnaire.

A parent or guardian should answer the following questions:

Question 1 of 3

Is the child or teen 5 to 17 years old?

Question 2 of 3

Is the child or teen generally healthy?

Certain stable chronic medical conditions may be allowed.

Question 3 of 3

Has the child or teen been diagnosed with Lyme disease in the past 3 months?

We're sorry, but you are not eligible at this time...

Thank you so much for your interest in our Lyme Disease vaccine study and for answering our questions.

There may be other Pfizer research studies enrolling in your area in the future. If you would like to be notified about future research opportunities, we will collect your name, phone number, and email address so that a study representative may contact you about other research studies. Your contact information will not be used for any other purposes.

The individual responses you've provided will be used by Pfizer, or our partners supporting this study, to look for areas of improvement such as revising the criteria for participation in this study. Pfizer study team members and our partners will have access to reports containing aggregated data that will not be directly linked back to you. All information is stored on servers in the United States.

So far - So good!

Please enter your information below to find a study location near you. By submitting this form, you confirm that you are at least 18 years of age (or the legal age of consent in your state if it is over 18) and that Pfizer or our partners may contact you about information related to research studies enrolling in your area. Once you select a site, the research study staff will contact you to see if you qualify to enroll.

Choose a Location

Please select a research site near you. If you don't see a site near you, then select "The sites listed here are not convenient for me." Study locations are being added regularly. A study representative will call you if a research site becomes available in your area.

Certified Research Associates

3767 Luker Road

Cortland, New York 13045

NaN Mi

Corning Center for Clinical Research

2977 Westinghouse Road

Horseheads, New York 14845

NaN Mi

Kentucky Pediatric & Adult Research

201 South 5th Street

Bardstown, Kentucky 40004

NaN Mi

Clinical Research Prime

187 East 13th Street

Idaho Falls, Idaho 83404

NaN Mi

Pediatric Research of Charlottesville

1011 East Jefferson Street

Charlottesville, Virginia 22902

NaN Mi

Preferred Primary Care Physicians

140 Curry Hollow Road

Pittsburgh, Pennsylvania 15236

NaN Mi

Aventiv Research

99 North Brice Road

Columbus, Ohio 43213

NaN Mi

The sites listed here are not convenient for me.

We're sorry, but you are not eligible at this time...

Please enter your information below if you would like to be contacted about future clinical research opportunities. By submitting this form, you confirm that you are at least 18 years of age (or the legal age of consent in your state if it is over 18) and that Pfizer or our partners may contact you about information related to research studies enrolling in your area.